What Causes ALS ?

Exploring the science behind a complex disease.

While the exact cause of ALS remains unknown in most cases, researchers believe a combination of genetic and environmental factors plays a role. About 5–10% of cases are inherited through gene mutations, while the rest are considered sporadic. Ongoing studies are investigating how disruptions in cell processes, inflammation, and protein buildup may contribute to motor neuron damage.

How ALS Progresses

From early symptoms to advanced stages

ALS typically begins with mild symptoms like muscle twitching or weakness in the limbs. As motor neurons degenerate, movement becomes increasingly limited, eventually affecting speech, swallowing, and breathing. The progression rate varies from person to person, but the disease is always progressive. Early diagnosis and symptom management can help improve quality of life.

The Urgency for Awareness

Why knowing about ALS is the first step toward a cure

ALS affects tens of thousands worldwide, yet remains underfunded and under-recognized. Raising awareness leads to earlier diagnoses, stronger community support, and more resources for scientific research. The more people understand ALS, the faster we can move toward breakthroughs that matter.